This is because the electron density of the gamma-polypeptide is mostly averaged out by its threefold crystallographic symmetry and only a few amino acids can be modeled.
2.
Chem . 2003 ), which identifies cross-rotation peaks consistent with non-crystallographic symmetry, was used in the structure determination of the enzyme dihydrofolate reductase-thymidylate synthase ( DHFR-TS ) from Cryptosporidium hominis, an important advancement in Cryptosporidium biology.
3.
This principle was later formalized by his student Woldemar Voigt ( 1850 1918 ) in 1885 : " the symmetry of the physical phenomenon is at least as high as the crystallographic symmetry ", which became a fundamental postulate of crystal physics known as "'Neumann s principle "' .
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